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Vaccination and MS

Learning objectives

This module was produced during the 2021 quarantine, where filming has been conducted remotely to adhere to social distancing guidelines. For this reason, please forgive a lower production quality than you are used to seeing from us.

This module is intended to help you:

Communicate the importance of vaccination in MS
Provide evidence-based guidance to patients on vaccinations and risk of MS and relapse
Ensure that your patients have the appropriate vaccinations according to the type of DMT they are receiving

Vaccination and MS

Vaccination in MS is an important topic because infections can increase relapse risk and certain DMTs can increase infection risk. In this module, both these points are discussed as well as highlighting the guidelines for the use of different vaccinations in patients on certain DMTs.

Length
12 min course

Job code
NPS-TPE-NP-00245

By around what % does high-efficacy therapy increase risk of infection-related physician claims for patients with MS compared with those not exposed to treatment?

Select the correct answer(s)

A study showed that high-efficacy DMTs were associated with an approximately 50% increased risk of infection-related physician claims for patients with MS compared with the untreated MS group.¹

When should the vaccination status of a person with MS be established?

Click on the correct point in the timeline

Which of these DMTs have a recommendation from either the FDA/EMA or Zrzavy et al. for a varicella-zoster virus vaccination prior to initiation if immunity has not been established?

Select the correct answer(s)

Based on data from post-marketing analysis, Zrzavy et al. recommend a human papillomavirus vaccination before initiation of which two DMTs?

Select the correct answer(s)

Reports of warts and cervical dysplasia in people taking certain immunosuppressive DMTs, lead to HPV vaccination being recommended by Zrzavy et al. for patients about to start fingolimod and alemtuzumab.¹

Which of these are true for the use of live-attenuated vaccines?

Select the correct answer(s)

The timing of vaccination is important for people with MS. Vaccines should be given...

Select the correct answer(s)

*It is recommended that vaccinations should not be given during a relapse because relapses sometimes require treatment with high-dose corticosteroids.²

Vaccination and MS

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Please rotate your device to landscape

For the best learning experience, we recommend to use a desktop device.

Vaccination and MS

Learning objectives

Please click continue to proceed.

Systemic infection is associated with increased risk of relapse — true or false?

Select the correct answer

Please click continue to proceed.

Which of these vaccines have been shown to not increase the risk of MS relapse?

Select the correct answer(s)

By around what % does high-efficacy therapy increase risk of infection-related physician claims for patients with MS compared with those not exposed to treatment?

Select the correct answer(s)

A study showed that high-efficacy DMTs were associated with an approximately 50% increased risk of infection-related physician claims for patients with MS compared with the untreated MS group.1

When should the vaccination status of a person with MS be established?

Click on the correct point in the timeline

Which of these DMTs have a recommendation from either the FDA/EMA or Zrzavy et al. for a varicella-zoster virus vaccination prior to initiation if immunity has not been established?

Select the correct answer(s)

Based on data from post-marketing analysis, Zrzavy et al. recommend a human papillomavirus vaccination before initiation of which two DMTs?

Select the correct answer(s)

Reports of warts and cervical dysplasia in people taking certain immunosuppressive DMTs, lead to HPV vaccination being recommended by Zrzavy et al. for patients about to start fingolimod and alemtuzumab.1

Which of these are true for the use of live-attenuated vaccines?

Select the correct answer(s)

The timing of vaccination is important for people with MS. Vaccines should be given...

Select the correct answer(s)

*It is recommended that vaccinations should not be given during a relapse because relapses sometimes require treatment with high-dose corticosteroids.2

Congratulations!

You have completed module 8

Links and downloadable elements

Vaccination and MS

The benefits of early DMT in relapsing–remitting MS

Disability progression

Systemic infection is associated with
increased risk of relapse — true or false?

Which of these vaccines have been shown
to not increase the risk of MS relapse?

A study showed that high-efficacy DMTs were associated with an approximately 50% increased risk of infection-related physician claims for patients with MS compared with the untreated MS group.¹

Reports of warts and cervical dysplasia in people taking certain immunosuppressive DMTs, lead to HPV vaccination being recommended by Zrzavy et al. for patients about to start fingolimod and alemtuzumab.¹

*It is recommended that vaccinations should not be given during a relapse because relapses sometimes require treatment with high-dose corticosteroids.²